Web MD.

FEMALES:

15 Cancer Symptoms Women Ignore
WebMD uncovers common cancer warning signs women often overlook.
By Kathleen Doheny
WebMD FeatureReviewed by Louise Chang, MDWomen tend to be more vigilant than men about getting recommended health checkups and cancer screenings, according to studies and experts.

They're generally more willing, as well, to get potentially worrisome symptoms checked out, says Mary Daly, MD, oncologist and head of the department of clinical genetics at Fox Chase Cancer Center in Philadelphia.

But not always. Younger women, for instance, tend to ignore symptoms that could point to cancer. "They have this notion that cancer is a problem of older people," Daly tells WebMD. And they're often right, but plenty of young people get cancer, too.

Of course, some women are as skilled as men are at switching to denial mode. "There are people who deliberately ignore their cancer symptoms," says Hannah Linden, MD, a medical oncologist. She is a joint associate member of the Fred Hutchinson Cancer Research Center and associate professor of medicine at the University of Washington School of Medicine, Seattle. It's usually denial, but not always, she says. "For some, there is a cultural belief that cancer is incurable, so why go there."

Talking about worrisome symptoms shouldn't make people overreact, says Ranit Mishori, MD, an assistant professor of family medicine at the Georgetown University School of Medicine in Washington, D.C. "I don't want to give people the impression they should look for every little thing," she says.

With that healthy balance between denial and hypochondria in mind, WebMD asked experts to talk about the symptoms that may not immediately make a woman worry about cancer, but that should be checked out. Read on for 15 possible cancer symptoms women often ignore.

No. 1: Unexplained Weight Loss
Many women would be delighted to lose weight without trying. But unexplained weight loss -- say 10 pounds in a month without an increase in exercise or a decrease in food intake -- should be checked out, Mishori says.

"Unexplained weight loss is cancer unless proven not," she says. It could, of course, turn out to be another condition, such as an overactive thyroid.

Expect your doctor to run tests to check the thyroid and perhaps order a CT scan of different organs. The doctor needs to "rule out the possibilities, one by one," Mishori says.

No. 2: Bloating
Bloating is so common that many women just live with it. But it could point to ovarian cancer. Other symptoms of ovarian cancer include abdominal pain or pelvic pain, feeling full quickly -- even when you haven't eaten much -- and urinary problems, such as having an urgent need to go to the bathroom.

If the bloating occurs almost every day and persists for more than a few weeks, you should consult your physician. Expect your doctor to take a careful history and order a CT scan and blood tests, among others.

No. 3: Breast Changes
Most women know their breasts well, even if they don't do regular self-exams, and know to be on the lookout for lumps. But that's not the only breast symptom that could point to cancer. Redness and thickening of the skin on the breast, which could indicate a very rare but aggressive form of breast cancer, inflammatory breast cancer, also needs to be examined, Linden says. "If you have a rash that persists over weeks, you have to get it evaluated," she says.

Likewise, if the look of a nipple changes, or if you notice discharge (and aren’t breastfeeding), see your doctor. "If it's outgoing normally and turns in," she says, that's not a good sign. "If your nipples are inverted chronically, no big deal." It's the change in appearance that could be a worrisome symptom.

If you have breast changes, expect your doctor to take a careful history, examine the breast, and order tests such as a mammogram, ultrasound, MRI, and perhaps a biopsy.

No. 4: Between-Period Bleeding or Other Unusual Bleeding
''Premenopausal women tend to ignore between-period bleeding," Daly says. They also tend to ignore bleeding from the GI tract, mistakenly thinking it is from their period. But between-period bleeding, especially if you are typically regular, bears checking out, she says. So does bleeding after menopause, as it could be a symptom of endometrial cancer. GI bleeding could be a symptom of colorectal cancer.

Think about what's normal for you, says Debbie Saslow, PhD, director of breast and gynecologic cancer at the American Cancer Society in Atlanta. "If a woman never spots [between periods] and she spots, it's abnormal for her. For someone else, it might not be."

"Endometrial cancer is a common gynecologic cancer," Saslow says. "At least three-quarters who get it have some abnormal bleeding as an early sign."

Your doctor will take a careful history and, depending on the timing of the bleeding and other symptoms, probably order an ultrasound or biopsy.

No. 5: Skin Changes
Most of us know to look for any changes in moles -- a well-known sign of skin cancer. But we should also watch for changes in skin pigmentation, Daly says.

If you suddenly develop bleeding on your skin or excessive scaling, that should be checked, too, she says. It's difficult to say how long is too long to observe skin changes before you go to the doctor, but most experts say not longer than several weeks. 

No. 6: Difficulty Swallowing
If you have difficulty swallowing, you may have already changed your diet so chewing isn't so difficult, perhaps turning to soups or liquid foods such as protein shakes.

But that difficulty could be a sign of a GI cancer, such as in the esophagus, says Leonard Lichtenfeld, MD, deputy chief medical officer at the American Cancer Society.

Expect your doctor to take a careful history and order tests such as a chest X-ray or exams of the GI tract.

No. 7: Blood in the Wrong Place
If you notice blood in your urine or your stool, don’t assume it's from a hemorrhoid, says Mishori. "It could be colon cancer."

Expect your doctor to ask questions and perhaps order testing such as a colonoscopy, an exam of the colon to look for cancer.

Seeing blood in the toilet bowl may actually be from the vagina if a woman is menstruating, Mishori says. But if not, it should be checked to rule out bladder or kidney cancer, she says.

Coughing up blood should be evaluated, too. One occasion of blood in the wrong place may not point to anything, Mishori says, but if it happens more than once, go see your doctor.

No. 8: Gnawing Abdominal Pain and Depression
Any woman who's got a pain in the abdomen and is feeling depressed needs a checkup, says Lichtenfeld. Some researchers have found a link between depression and pancreatic cancer, but it's a poorly understood connection.

No. 9: Indigestion
Women who have been pregnant may remember the indigestion that occurred as they gained weight. But indigestion for no apparent reason may be a red flag.

It could be an early clue to cancer of the esophagus, stomach, or throat.

Expect your doctor to take a careful history and ask questions about the indigestion before deciding which tests to order, if any.

No. 10: Mouth Changes
Smokers should be especially alert for any white patches inside the mouth or white spots on the tongue, according to the American Cancer Society. Both can point to a precancerous condition called leukoplakia that can progress to oral cancer.

Ask your dentist or doctor to take a look and decide what should be done next.

No. 11: Pain
As people age they seem to complain more of various aches and pains, but pain, as vague as it may be, can also be an early symptom of some cancers, although most pain complaints are not from cancer.

Pain that persists and is unexplained needs to be checked out. Expect your physician to take a careful history, and based on that information decide what further testing, if any, is needed.

No. 12: Changes in the Lymph Nodes
If you notice a lump or swelling in the lymph nodes under your armpit or in your neck -- or anywhere else -- it could be worrisome, Linden says.

"If you have a lymph node that gets progressively larger, and it's [been] longer than a month, see a doctor," she says. Your doctor will examine you and figure out any associated issues (such as infection) that could explain the lymph node enlargement.

If there are none, your doctor will typically order a biopsy.

No. 13: Fever
If you have a fever that isn't explained by influenza or other infection, it could point to cancer. Fevers more often occur after cancer has spread from its original site, but it can also point to early blood cancers such as leukemia or lymphoma, according to the American Cancer Society.

Other cancer symptoms can include jaundice, or a change in the color of your stool.

Expect your doctor to conduct a careful physical exam and take a medical history, and then order tests such as a chest X-ray, CT scan, MRI, or other tests, depending on the findings.

No. 14: Fatigue
Fatigue is another vague symptom that could point to cancer -- as well as a host of other problems. It can set in after the cancer has grown, but it may also occur early in certain cancers, such as leukemia or with some colon or stomach cancers, according to the American Cancer Society.

No. 15: Persistent Cough
Coughs are expected with colds, the flu, allergies, and sometimes are a side effect of medications. But a very prolonged cough -- defined as lasting more than three or four weeks -- should not be ignored, Mishori says.

You would expect your doctor to take a careful history, examine your throat, check out your lung functioning and perhaps order X-rays, especially if you are a smoker.

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MALES:

15 Cancer Symptoms Men Ignore
Men, heed these possible clues and find cancer early, when it's more treatable.
By Kathleen Doheny
WebMD FeatureReviewed by Louise Chang, MDSome men are notorious foot-draggers, especially when it comes to scheduling doctor visits. That’s unfortunate. Routine preventive care can find cancer in men and other diseases in the early stages, when there are more options for treatment and better chances of a cure. Some men, though, would never go to the doctor except for the women in their life. According to Leonard Lichtenfeld, MD, deputy chief medical officer for the national office of the American Cancer Society, women are often the ones who push men to get screened for cancer.

Experts say that men could benefit greatly by being alert to certain cancer symptoms that indicate a trip to the doctor’s office sooner rather than later. Some of those cancer symptoms in men are specific. They involve certain body parts and may even point directly to the possibility of cancer. Other symptoms are more vague. For instance, pain that affects many body parts could have dozens of explanations and may not be cancer. But that doesn’t mean you can rule out cancer without seeing a doctor.

Cancer Symptom in Men No. 1: Breast Mass
If you’re like most men, you’ve probably never considered the possibility of having breast cancer. Although it’s not common, it is possible. "Any new mass in the breast area of a man needs to be checked out by a physician," Lichtenfeld says.

In addition, the American Cancer Society identifies several other worrisome signs involving the breast that men as well as women should take note of. They include:

Skin dimpling or puckering
Nipple retraction
Redness or scaling of the nipple or breast skin
Nipple discharge
When you consult your physician about any of these signs, expect him to take a careful history and do a physical exam. Then, depending on the findings, the doctor may order a mammogram, a biopsy, or other tests.

Cancer Symptom in Men No. 2: Pain
As they age, people often complain of more aches and pains. But pain, as vague as it may be, can be an early symptom of some cancers although most pain complaints are not from cancer.

Any pain that persists, according to the American Cancer Society, should be checked out by your physician. The doctor can take a careful history, get more details, and then decide whether further testing is necessary, and if so what kind. If it's not cancer, you will still benefit from the visit to the office. That’s because the doctor can work with you to find out what's causing the pain and help you know what to do about it.

Cancer Symptom in Men No. 3: Changes in the Testicles
Testicular cancer occurs most often in men aged 20 to 39. The American Cancer Society recommends that men get a testicular exam by a doctor as part of a routine cancer-related checkup. And some doctors suggest a monthly self-exam.

Cancer Symptom in Men No. 3: Changes in the Testicles continued...
Yu tells WebMD that being aware of troublesome testicular symptoms between exams is wise. "Any change in the size of the testicles, such as growth or shrinkage," Yu says, “should be a concern.” In addition, swelling or a lump should not be ignored. Nor should a feeling of heaviness in the scrotum. Some testicular cancers occur very quickly. So early detection is especially crucial. Yu recalls a young man who waited until his testicle was the size of a grapefruit before coming in for help. "If you feel a hard lump of coal [in your testicle], get it checked right away," Yu says.

Your doctor will do a testicular exam and an overall assessment of your health. If cancer is suspected, blood tests may be ordered. You may undergo an ultrasound examination of your scrotum. Your doctor may also decide to do a biopsy, taking a tiny sample of testicular tissue to examine it for cancer.

Cancer Symptom in Men No. 4: Changes in the Lymph Nodes
If you notice a lump or swelling in the lymph nodes under your armpit or in your neck -- or anywhere else -- it could be a reason for concern, says Hannah Linden, MD. Linden is a medical oncologist and an associate professor of medicine at the University of Washington School of Medicine. She is also a joint associate member of the Fred Hutchinson Cancer Research Center in Seattle, Wash. "If you have a lymph node that gets progressively larger, and it's been longer than a month, see a doctor," she says.

Your doctor will examine you and figure out any associated issues that could explain the lymph node enlargement, such as infection. If there is no infection, a doctor will typically order a biopsy.

Cancer Symptom in Men No. 5: Fever
If you've got an unexplained fever, it may indicate cancer. It could also be a sign of pneumonia or some other illness that needs treatment.

Most cancers will cause fever at some point. Often, fever occurs after the cancer has spread from its original site and invaded another part of the body. But it can also be caused by blood cancers such as lymphoma or leukemia, according to the American Cancer Society. It’s best not to ignore a fever that can’t be explained. Check with your doctor to find out what might be causing it and if anything needs to be done.

Cancer Symptom in Men No. 6: Weight Loss Without Trying
Unexpected weight loss is a concern, Lichtenfeld says. "Most of us don't lose weight easily." He's talking about more than simply a few pounds from a stepped up exercise program or to eating less because of a busy schedule. If a man loses more than 10% of his body weight in a short time period such as a matter of weeks, it’s time to see the doctor, he says.

Your doctor will do a general physical, ask you questions about your diet and exercise, and ask about other symptoms. Based on that information, the doctor will decide what other tests are needed.

Cancer Symptom in Men No. 7: Gnawing Abdominal Pain and Depression
“Any guy who's got a pain in the abdomen and is feeling depressed needs a checkup,” says Lichtenfeld. Experts have found a link between depression and pancreatic cancer. Other symptoms can include jaundice or a change in the stool color, often a gray color.

Expect your doctor to do a careful physical exam and take a history. The doctor may then order tests such as a chest X-ray, CT scan, MRI, and, possibly, other scans and tests.

Cancer Symptom in Men No. 8: Fatigue
Fatigue is another vague symptom that could point to cancer in men. But a host of other problems could cause it as well. Like fever, fatigue can set in after the cancer has grown. But it may also happen early in cancers such as leukemia or with some colon or stomach cancers, according to the American Cancer Society.

If you often feel extremely tired and it doesn’t get better with rest, check with your doctor. The doctor will evaluate it along with any other symptoms in order to determine what’s causing it and what can be done about it.

Cancer Symptom in Men No. 9: Persistent Cough
Coughs are expected, of course, with colds, the flu, and allergies. They are also sometimes a side effect of a medication. But a very prolonged cough -- defined as lasting more than three or four weeks -- should not be ignored, says Ranit Mishori, MD, assistant professor and director of the family medicine clerkship at Georgetown University School of Medicine in Washington, D.C. That kind of cough warrants a visit to the doctor. It could be a symptom of cancer, or it could indicate some other problem such as chronic bronchitis or acid reflux.

Your doctor will take a careful history, examine your throat, check how your lungs are functioning, and, especially if you are a smoker, perhaps order X-rays. Once the reason for the coughing is identified, the doctor will work with you to determine a treatment plan.

Cancer Symptom in Men No. 10: Difficulty Swallowing
Some men may report trouble swallowing but then learn to live with it, Lichtenfeld says. "Over time, they change their diet to a more liquid diet. They start to drink more soup." But swallowing difficulties, he says, could be a sign of a GI cancer, such as cancer of the esophagus.

Let your doctor know if you are having trouble swallowing. Your doctor will take a careful history and possibly order a chest X-ray. The doctor may also send you to a specialist for an upper endoscopy to examine your esophagus and upper GI tract.

Cancer Symptom in Men No. 11: Changes in the Skin
You should be alert to not only changes in moles -- a well-known sign of potential skin cancer -- but also changes in skin pigmentation, says Mary Daly, MD. Daly is an oncologist and head of the department of clinical genetics at the Fox Chase Cancer Center in Philadelphia.

She also says that suddenly developing bleeding on your skin or excessive scaling are reasons to check with your doctor. It's difficult to say how long is too long to observe skin changes, but most experts say not to wait longer than several weeks.

To find out what’s causing the changes, your doctor will take a careful history and perform a careful physical exam. The doctor may also order a biopsy to rule out cancer.

Cancer Symptom in Men No. 12: Blood Where It Shouldn't Be
“Anytime you see blood coming from a body part where you've never seen it before, see a doctor,” Lichtenfeld says. "If you start coughing or spitting up blood, have blood in the bowel, or blood in the urine, it’s time for a doctor visit.”

Mishori says it’s a mistake to assume blood in the stool is simply from a hemorrhoid. "It could be colon cancer," he says.

Your doctor will ask you questions about your symptoms. The doctor may also order tests such as a colonoscopy, which is an examination of the colon using a long flexible tube with a camera on one end. The purpose of a colonoscopy is to identify any signs of cancer or precancer or to identify what else might be causing the bleeding.

Cancer Symptom in Men No. 13: Mouth Changes
If you smoke or chew tobacco, you need to be especially alert for any white patches inside your mouth or white spots on your tongue. Those changes may indicate leukoplakia, a precancerous area that can occur with ongoing irritation. The condition can progress to oral cancer.

You should report the changes to your doctor or dentist. The dentist or doctor will take a careful history, examine the changes, and then decide what other tests might be needed.

Cancer Symptom in Men No. 14: Urinary Problems
As men age, urinary problems become more frequent, says Yu. He's talking about the urge to urinate more often, a sense of urgency, and a feeling of not completely emptying the bladder. "Every man will develop these problems as he gets older," he says. "But if you notice it and it concerns you, you should seek attention." That's especially true if the symptoms get worse.

Your doctor will do a digital rectal exam, which will tell him whether the prostate gland is enlarged. The gland often enlarges as a man ages. It’s typically caused by a noncancerous condition called benign prostatic hyperplasia or BPH. Your doctor may also order a blood test to check the level of prostate-specific antigen or PSA. PSA is a protein produced by the prostate gland, and the test is used to help determine the possibility of prostate cancer. If the doctor notices abnormalities in the prostate or if the PSA is higher than it should be, your doctor may refer you to an urologist and perhaps order a biopsy.

Cancer Symptom in Men No. 15: Indigestion
A lot of guys, especially as they get older, think "heart attack" when they get bad indigestion, even if they've just eaten and drunk their way through a marathon Super Bowl viewing. But persistent indigestion could point to cancer of the esophagus, throat, or stomach and should be reported to your doctor.

Your doctor will take a careful history and ask questions about the indigestion episodes. Based on the history and your answers to the questions, the doctor will decide what tests are needed.